A multi-institutional consortium dedicated to accelerating therapeutic discovery for Alzheimer's disease and related dementias through innovative knowledge integration and AI-driven insights.
The ADiKA Consortium is revolutionizing AD/ADRD research by creating the world's most comprehensive, FAIR-compliant knowledge base that integrates multi-scale biomedical data with real-world clinical evidence.
Our mission is to accelerate therapeutic discovery through innovative AI-driven hypothesis generation, federated learning approaches, and community-driven research collaboration.
Ensuring data is Findable, Accessible, Interoperable, and Reusable
Advanced federated learning without compromising patient privacy
Transparent, reproducible research with community engagement
Our consortium focuses on four key research areas that together create a comprehensive approach to AD/ADRD therapeutic discovery.
Building comprehensive, ontology-aligned knowledge graphs that integrate genomic, proteomic, phenotypic, and clinical data from multiple sources.
Leveraging large language models and graph neural networks to identify novel therapeutic targets and drug repurposing opportunities.
Developing privacy-preserving machine learning approaches that enable multi-institutional collaboration without compromising patient data.
Building an open, collaborative platform that enables researchers to share knowledge, validate hypotheses, and accelerate discovery.
Our consortium has published groundbreaking research in top-tier journals, advancing the field of AD/ADRD therapeutic discovery.
We are currently verifying and curating peer-reviewed publications from the ADiKA Consortium related to knowledge graphs, biomedical data integration, and machine learning-based drug discovery.
Three groundbreaking papers from our consortium leaders (Xiaoqian Jiang, Cui Tao, Fei Wang, and Jiang Bian) will be featured here with direct links to verified publications.
For latest research updates, visit PubMed to search publications by our consortium members.
Be part of the future of AD/ADRD research. Whether you're a researcher, clinician, or institution, there are many ways to get involved in our consortium.